hrp0084p1-60 | DSD | ESPE2015

Insight into the Human Ovarian Sex Development Networks

Bouazzi Leila , Franco Mariangela , Eid Wassim , Meyer-Boni Monika , Sproll Patrick , Maret Alexander , Lauber-Biason Anna

Background: Ovarian sex differentiation network involves a panoply of interacting factors. Yet, no single sex-determining factor has been identified to be an equivalent of SRY or SOX9 in the testis. Recently, data suggested CBX2 as a pioneer regulator promoting testis development. In addition to its implication in ovary pathway differentiation which remains unclear.Objective and hypotheses: To deepen our understanding of the regulatory network that under...